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地球物理 1

岩性 1

无监督领域自适应；优化步骤；跨域判别表示；语义判别 1

激光雷达 1

电磁感应 1

频率分集阵列；欺骗干扰；距离角度耦合；和差波束；双波束 1

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The role of natriuretic peptide precursor A gene polymorphism in the development of coronary heart disease in Chinese Han population?

Ripen NSENGA MD, Longxian CHENG PhD, Mei’an HE PhD, Tangchun WU PhD,

《医学前沿（英文）》 2009年 第3卷 第4期   页码 437-442 doi: 10.1007/s11684-009-0074-x

摘要： Natriuretic peptide precursor A (NPPA) is synthesized, stored, and released by atrial myocytes. Previous studies have shown that NPPA plays a significant role in the regulation of coronary circulation and in atherosclerosis. Rs5065 NPPA gene polymorphism leads to the translation of NPPA with two additional arginines and has been suggested to be associated with salt-sensitive hypertension. The purpose of the present study was to investigate the relationship between the rs5065 NPPA gene polymorphism and the risk of coronary heart disease (CHD) in Chinese Han population. We genotyped the single nucleotide polymorphism (SNP) rs5065 NPPA in the human NPPA gene in 1861 sex- and age-matched subjects, comprising of 904 CHD cases and 957 controls of Chinese Han population. Genotyping of SNP was performed with Taqman SNP allelic discrimination assays by means of an ABI 7900HT. Our study showed that the frequencies of rs5065 NPPA C allele in the case and the control groups were 0.012 and 0.005, respectively. There was significant difference in C allele frequency distribution between the two groups (OR=2.607, 95% CI: 1.197−5.678, =0.012). In the case group, there was significant difference between smokers and nonsmokers with subjects carrying C allele (=0.037), and no significant difference in gender, age, fasting total cholesterol (TC), triglycerides (TG), fasting plasma glucose (FPG), body mass index (BMI), and blood pressure (BP) between the cases and the controls (>0.05). Our results suggest that the C allele of rs5065 NPPA gene polymorphism may be associated with the risk of CHD.

关键词： natriuretic peptide precursor A     coronary heart disease     gene polymorphism     allelic discrimination     polymorphism     single nucleotide    

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无监督域自适应的动态参数化学习 Research Article

蒋润华1,2,韩亚洪1,2

《信息与电子工程前沿（英文）》 2023年 第24卷 第11期   页码 1616-1632 doi: 10.1631/FITEE.2200631

摘要： 无监督领域自适应通过学习域不变表示实现神经网络从有标签数据组成的源域到无标签数据组成的目标域迁移。近期研究通过直接匹配这两个域的边缘分布实现这一目标。然而，已有研究大多数忽略域对齐和语义判别学习之间的动态平衡，因此容易受负迁移和异常样本影响。为解决这些问题，引入动态参数化学习框架。首先，通过探索领域级语义知识，提出动态对齐参数自适应地调整域对齐和语义判别学习的优化过程。此外，为获得判别能力强和域不变的表示，提出在源域和目标域上对齐优化过程。本文通过综合实验证明了所提出方法的有效性，并在3个视觉任务的7个数据集上进行广泛比较，证明可行性。

关键词： 无监督领域自适应；优化步骤；跨域判别表示；语义判别    

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Quality evaluation of lightweight cellular concrete by an ultrasound-based method

Xin LIU; Dongning SUN; Jinhe LIAO; Zhiwei SHAO; Yunqiang SHI; Siqing ZHANG; Yunlong YAO; Baoning HONG

《结构与土木工程前沿（英文）》 2022年 第16卷 第9期   页码 1170-1182 doi: 10.1007/s11709-022-0874-5

摘要： The accuracy of subgrade quality evaluation is important for road safety assessment. Since there is little research work devoted to testing lightweight cellular concrete (LCC) by an ultrasound-based method, the quantitative relation between ultrasonic testing results and the quality of LCC subgrade is not well understood. In this paper, the quality of LCC subgrade was evaluated with respect to compressive strength and crack discrimination. The relation between ultrasonic testing results and LCC quality was explored through indoor tests. Based on the quantitative relation between ultrasonic pulse velocity and compressive strength of LCC, a fitting formula was established. Moreover, after the LCC became cracked, the ultrasonic pulse velocity and ultrasonic pulse amplitude decreased. After determining the lower limiting values of the ultrasonic pulse velocity and ultrasonic pulse amplitude through the statistical data, it could be calculated whether there were cracks in LCC subgrade. The ultrasonic testing results showed that the compressive strength of the LCC subgrade was suitable for purpose and there was no crack in the subgrade. Then core samples were taken from the subgrade. Comparisons between ultrasonic testing results of subgrade and test results of core samples demonstrated a good agreement.

关键词： lightweight cellular concrete     subgrade     ultrasound testing     quality evaluation     crack discrimination    

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基于距离、角度定位的频率分集阵列欺骗干扰鉴别方法 Article

Zhao-jian ZHANG, Jun-wei XIE, Chuan SHENG, Zhun TANG

《信息与电子工程前沿（英文）》 2017年 第18卷 第9期   页码 1437-1446 doi: 10.1631/FITEE.1601577

摘要： 针对电子对抗中的欺骗干扰鉴别问题，提出了基于频率分集阵列（frequency diverse array, FDA）的干扰鉴别方法。FDA波束具有距离—角度二维耦合特性，当波束聚焦距离与真实目标不一致时，会产生角误差信号，即干扰角度在相控阵中与真实目标一致，而在FDA中与真实目标不一致。因此，利用相控阵和FDA分别进行参数测量，比对测量结果即可实现干扰鉴别。提出了基于FDA进行干扰鉴别的具体流程，给出了两种双波束测量的实现方案，并对各方案的目标检测及参数估计性能进行了理论分析。仿真结果证明了该方法的有效性。

关键词： 频率分集阵列；欺骗干扰；距离角度耦合；和差波束；双波束    

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利用机载激光雷达和近地表地球物理方法空间识别复杂低幅度第四纪硅质碎屑岩层——以美国得克萨斯滨海平原为例 Article

Jeffrey G. Paine,Edward W. Collins,Lucie Costard

《工程（英文）》 2018年 第4卷 第5期   页码 676-684 doi: 10.1016/j.eng.2018.09.005

摘要：

保存在全球滨海平原上的沉积单元控制着浅地层岩性分布，这对基础设施的设计和建设至关重要，同时也是许多第四纪冰期—间冰期循环中发生大规模气候变化的重要信息库。我们对这些沉积单元的横纵向岩性、地层复杂性及其对气候和海平面变化的响应知之甚少，因此很难预测岩性分布，以及将发展历史、未来气候和海平面变化置于同一自然地质环境中。传统上在低幅度滨海平原上描绘的第四纪硅质碎屑沉积单元建立在航拍图和低分辨率地形图的基础上。低幅度和低曝光率影响了观测的准确性和精确性。高分辨率机载激光雷达探测、地表地球物理勘探和地球物理测井正被用于识别得克萨斯州滨海平原上第四纪地层岩性单元的精确横纵向边界。地表和井中电导率测量能从泥质泛滥平原、三角洲平原和河道沉积中区分出砂质障壁岛、河流和三角洲河道沉积物。井中电导率和自然伽马测井记录同样可以区分地下不同的岩性单元，并识别出可能在不同冰期- 间冰期阶段分离的沉积单元的侵蚀不整合面。从机载激光雷达探测获得的高分辨率数字高程模型揭示了以前不为人知的地形细节，有助于识别地表特征，如砂质通道、富含黏土的河间沉积和更新世障壁岛上的堆积特征。在低幅度滨海平原环境中识别岩性和地层分布的最佳方法是：①首先使用激光雷达探测生成详细的高程模型；②基于激光雷达数据和航拍图的初步定位，选择性进行地表采样和地球物理探测；③在激光雷达和地表探测完成后，选择关键位置进行钻孔取样、测井和分析。

关键词： 岩性     地球物理     电磁感应     激光雷达    

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Depletion of conventional mature B cells and compromised specific antibody response in bovine immunoglobulin μ heavy-chain transgenic mice

Min ZHANG,Xueqian CHENG,Dan CHU,Jingwen LIANG,Yi SUN,Li MA,Beilei XU,Min ZHENG,Meili WANG,Liming REN,Xiaoxiang HU,Qingyong MENG,Ran ZHANG,Ying GUO,Yunping DAI,Robert AITKEN,Ning LI,Yaofeng ZHAO

《农业科学与工程前沿（英文）》 2014年 第1卷 第2期   页码 158-173 doi: 10.15302/J-FASE-2014015

摘要： In this study, we introduced the bovine immunoglobulin μ heavy-chain gene (the orphaned gene on BTA11) into mouse germline cells. Bovine IgM was highly expressed in selected transgenic lines, and it largely inhibited rearrangements of the endogenous immunoglobulin heavy chain (IgH) genes in these lines. The forced expression of bovine IgM resulted in reduced numbers of pro- and pre-B cells but increased the number of immature B cells in the transgenic mice. Bovine IgM-expressing B cells can migrate from the bone marrow to the spleen, but most of the cells are arrested at the T1 transitional B cell stage, leading to a significantly lower number of T2 transitional and mature B cells in the spleen. Although the serum concentrations of endogenous IgM and IgG in the transgenic mice were significantly decreased, the IgA levels were slightly increased compared to the WT mice. The bovine IgM level in the serum was only one-tenth to one-fifth of that of endogenous mouse IgM, suggesting that most of the serum immunoglobulin were contributed by endogenous IgH gene-expressing B cells. These transgenic mice also exhibited a lower frequency of unique complementarity determining region 3 (CDR3) sequences in their VH repertoire and Vκ repertoire but exhibited an increased frequency of unique CDR3 in their Vλ repertoire. Compared to the WT mice, the transgenic mice had a significantly higher percentage of mouse IgM-expressing B cells that expressed λ chains. Finally, we showed that the transgenic mice were deficient in a specific antibody response to antigen stimulation.

关键词： bovine Ig μ heavy-chain     transgenic mice     B cell development     allelic exclusion     immune response     Ig repertoire    

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标题 作者 时间 类型 操作

The role of natriuretic peptide precursor A gene polymorphism in the development of coronary heart disease in Chinese Han population?

Ripen NSENGA MD, Longxian CHENG PhD, Mei’an HE PhD, Tangchun WU PhD,

期刊论文

无监督域自适应的动态参数化学习

蒋润华1,2,韩亚洪1,2

期刊论文

Quality evaluation of lightweight cellular concrete by an ultrasound-based method

Xin LIU; Dongning SUN; Jinhe LIAO; Zhiwei SHAO; Yunqiang SHI; Siqing ZHANG; Yunlong YAO; Baoning HONG

期刊论文

基于距离、角度定位的频率分集阵列欺骗干扰鉴别方法

Zhao-jian ZHANG, Jun-wei XIE, Chuan SHENG, Zhun TANG

期刊论文

利用机载激光雷达和近地表地球物理方法空间识别复杂低幅度第四纪硅质碎屑岩层——以美国得克萨斯滨海平原为例

Jeffrey G. Paine,Edward W. Collins,Lucie Costard

期刊论文

Depletion of conventional mature B cells and compromised specific antibody response in bovine immunoglobulin μ heavy-chain transgenic mice

Min ZHANG,Xueqian CHENG,Dan CHU,Jingwen LIANG,Yi SUN,Li MA,Beilei XU,Min ZHENG,Meili WANG,Liming REN,Xiaoxiang HU,Qingyong MENG,Ran ZHANG,Ying GUO,Yunping DAI,Robert AITKEN,Ning LI,Yaofeng ZHAO

期刊论文